



Dvanaest dobrih razloga da podržite Zakladu za zaštitu životinja Bestie iz Splita.
POMOZITE ZAKLADI BESTIE: MOLIM VAS DONIRAJTE!
Detalji za donacije:
Jednog lijepog sunčanog dana u ožujku, jedno sretno štene došetalo je u Jelsu popiti kavu sa svojim novim vlasnicima.




Dvanaest dobrih razloga da podržite Zakladu za zaštitu životinja Bestie iz Splita.
POMOZITE ZAKLADI BESTIE: MOLIM VAS DONIRAJTE!
Detalji za donacije:
Scientists say record-breaking heat is a reminder of how climate crisis is affecting lives
The fierce heat sweeping across Europe over the bank holiday weekend has beaten the UK’s all-time temperature record for May, with scorching highs of close to 35C.
A temperature of 33.5C was recorded at Heathrow airport on Monday lunchtime, according to provisional data from the Met Office, beating the previous May record that was set in 1922 and reached again in 1944. Later in the afternoon a temperature of 34.8C was recorded at London’s Kew Gardens.
Continue reading...
Charing, Challock and Molash worst affected, as South East Water says ‘technical failure at pumping station’ to blame
Hundreds of homes in Kent and Sussex have been left without water by a company that MPs recently accused of incompetence.
South East Water said the hot weather and extra demand for water meant it was having to pump more drinking water than usual to higher ground.
Continue reading...
Rain overwhelms sewer system in parts of US city, while temperatures in France break May record
New York City saw flash flooding on Wednesday, as large parts of Brooklyn and Queens received about 2in (50mm) of rainfall in as little as 20 minutes. Officials said the deluge caused water to flow into the sewer system at a rate of up to 6in an hour, quickly overwhelming an aged network that was designed to accommodate just 1.75in an hour.
Residents and commuters found themselves wading knee-deep through flood water that flowed with dangerous speed in places. One video showed a woman alighting from a bus losing her footing and being dragged along by the torrent of water. Several major roads were blocked, including the Long Island Expressway, and subway services were disrupted as water spilled into stations. Large amounts of mud and other debris was left behind; videos showed bags of rubbish being swept down streets along with loose litter.
Continue reading...
Most people have joyful memories of playing outside as children – and now wildlife charities are urging people to ‘rewild their inner child’
Climbing trees, squelching in mud, paddling in ponds or making dens in the woods – people’s memories of playing outside as children are often vivid and, a new poll has found, overwhelmingly positive, even those who remember falling in cowpats.
Almost 90% of UK adults had rosy memories of the excitement and the feeling of freedom that outdoor play had brought them, the survey found. However, almost half of adults now spend less than three hours a week in natural settings such as gardens, parks, fields or woods, according to the survey. For one in 10 it is less than one hour.
Continue reading...
Charter to be adopted along river’s entire catchment from Cambrian mountains to Chepstow and Bristol Channel
The entire catchment of the River Wye has been formally recognised as a living ecosystem with intrinsic rights in a charter, a UK first that campaigners hope will help save the highly polluted river.
The charter was celebrated at a community event at the Hay-on-Wye literary festival on Sunday. It includes the right to flow, to biodiversity, to be free from pollution, to be supported by a healthy catchment, to regenerate, and the right to be represented, described as a “significant step” towards protecting and restoring one of the UK’s most beloved rivers.
Continue reading...
Definition of green facilities made in 2022, before release of ChatGPT, says Action to Protect Rural Scotland
A Scottish government policy designed to encourage datacentres to build in Scotland could lead to a massive volume of carbon emissions being ignored, according to an analysis by a Scottish charity.
“Green datacentres” are at the heart of Scotland’s ambitions to develop economically. Enshrined in national policy, they are part of a larger, UK-wide effort to attract big AI investment to Scotland.
Continue reading...
Talybont, Ceredigion: On a crisp, post-rain morning, I take a walk among bright hawthorn blossom and the glittering pools of Cors Fochno
On the edge of Talybont, the small cemetery, kempt and cared for, overlooks the coast and the wild brown swathe of Cors Fochno (Borth Bog). A burial ground is perhaps an odd place to begin a walk, but, as a friend remarked, it’s infinitely better than ending one there.
The early rain has cleared so the air is crisp and the colours deep. In the foreground, grassland fields slope away towards the wild expanse of the bog, bounded by wooded hedgerows bright with hawthorn blossom. The first cut of silage has been secured, baled and removed, and a few cattle are grazing the aftermath with interest while red kites traverse overhead. The surface of the bog, marked here and there by glittering open pools, shimmers slightly in the heat of the day. Across the Afon Dyfi, the steep-faced sand dunes of Aberdyfi are visible before the eye is drawn further off to the line of hills that defines the Llŷn peninsula.
Continue reading...
Like so many Britons, I usually consult a weather app before venturing out of the house – and often cancel plans if I don’t like what I see. Here’s what happened when I went cold turkey for a week
When I heard on the radio that more than half of British people would consider cancelling an outing if they saw a 40% chance of rain all day on their weather app, I felt seen. I, too, am a slave to my app. Not that I would ever make a decision based on one whole-day percentage. I pore over three-hourly breakdowns for chances of rain versus minutes of sunshine. If rain is on the cards, I check the probable millimetres. Less than one? I may well throw caution to the wind. Speaking of which, wind speed and direction must also be considered, along with overall and “feels like” temperatures. For the cherry on top, I’ll compare notes with a loved one’s app if they use a different one, quietly mistrusting theirs, and simmering in silent rage if theirs wins.
I’ll admit, though, that my compulsion to check my app (I long ago chose WeatherPro, which I knew nothing about, but liked its layout and name) is borderline neurotic; I fret over probabilities and outfit appropriateness, when I could simply step outside for real-time hyper-local accuracy. I can lose procrastinatory hours consulting long-range forecasts, or checking the weather in Melbourne (where my sister lives) and holiday destinations I have no immediate plans to visit.
Continue reading...
Jay Morris denies experts’ claims that he violated ethics rules over land deals near the site of Meta’s Hyperion datacenter
This story is from Floodlight, a non-profit newsroom that investigates the powers stalling climate action
For more than two years, John “Jay” Morris, a Louisiana state senator, helped pave the way for Meta to build one of the world’s largest datacenters, called Hyperion, in Richland Parish.
Continue reading...
The state saw 33 tornadoes last year and severe flooding as researchers say links to climate change are undeniable
The tornado hit west Ann Arbor at 1.45am on 15 April, passing through Veterans Memorial park, where it knocked several mature oak trees and ripped up baseball field fences before setting its sights on a local ice rink.
“It came up through the parking lot and, in that time, the pressure differential between the tornado and the air inside the rink collapsed the wall,” said Scott Spooner, a manager at Ann Arbor Parks and Recreation.
Continue reading...
Nova predklinička studija otkrila je genetske i stanične adaptivne mehanizme koji potiču rezistenciju na KRAS inhibitore kod pacijenata s kolorektalnim karcinomom s mutacijom KRAS. Ovi rezultati sugeriraju da ciljanje ranih upalnih odgovora dodavanjem blokade TBK1 s inhibicijom KRAS-a može biti obećavajuća kombinirana strategija za prevladavanje rezistencije na liječenje.
Tradicionalno smatrana genetskim poremećajem uzrokovanim mutacijama u genima PKD1 i PKD2, autosomno dominantna policistična bolest bubrega (ADPKD) se sada redefinira prepoznavanjem kronične upale, infiltracije imunoloških stanica i imunoloških signalnih putova kao ključnih čimbenika koji doprinose progresiji bolesti.
Novo objavljeni pregledni članak ističe novu važnost imunoproteasoma u razvoju i napredovanju dijabetesa i njegovih širokog spektra komplikacija, nudeći nove perspektive o budućim terapijskim strategijama. Rezultati pozicioniraju ovaj specijalizirani proteinski kompleks kao ključni regulator upale, metabolizma i staničnog zdravlja.
Nova studija provedena u Italiji otkrila je da post prije i nakon kemoterapije, u usporedbi s redovitom prehranom, može pomoći u smanjenju razine inzulina i može poboljšati odgovor na liječenje kod osoba s visokostupanjskim seroznim rakom jajnika (HGSOC).
Rezultati nedavno objavljene studije pokazuju da agonisti GLP-1 receptora mogu smanjiti metastatsku progresiju određenih karcinoma povezanih s pretilošću, i to raka pluća, raka dojke, raka debelog crijeva i raka jetre. Osim toga, ekspresija GLP-1 receptora bila je povezana s ukupnim preživljavanjem, što sugerira da bi signalizacija GLP-1 mogla biti uključena u progresiju ovih karcinoma.
Kineski znanstvenici otkrili su novi mehanizam kojim Pim1 regulira diferencijaciju Th17 stanica putem mitohondrijskog metabolizma. Molekularnim docking probirom identificirali su nilotinib kao učinkovitog kandidata za lijek za liječenje upalnog artritisa ciljajući Pim1.
Osobe s teškom astmom obično se bore i s drugim zdravstvenim problemima, tvrdi nova studija. Gotovo sve osobe s astmom pate od barem jednog drugog većeg zdravstvenog problema, a većina pati od tri ili više, izvijestili su znanstvenici.
Znanstvenici s Medicinskom fakultetu Sveučilišta Rochester pomogli su transformirati neuroznanstvena istraživanja 2012. godine otkrićem glimfatičkog sustava, mreže u cijelom mozgu koja cirkulira cerebrospinalnu tekućinu kroz tkivo koje okružuje krvne žile kako bi pomogla u uklanjanju metaboličkog otpada. Sustav je posebno aktivan tijekom spavanja i od tada je postao središnji dio istraživanja Alzheimerove bolesti, Parkinsonove bolesti, moždanog udara, traumatske ozljede mozga i drugih neuroloških poremećaja.
Desetljeće dugo praćenje djece u Danskoj povezuje veću prenatalnu suplementaciju vitaminom D3 s jačim pamćenjem, ističući trudnoću kao mogući prozor za oblikovanje dječje kognitivne sposobnosti.
Gestacijski dijabetes snažan je faktor rizika za budući dijabetes tipa 2, čak i kod žena s normalnom tjelesnom težinom prije trudnoće, tvrdi nova studija. Stoga stručnjacii pozivaju na ranije testiranje i bolje praćenje.