




Chief scientist says dangerous heatwaves, which are getting more likely, ‘bring home the implications of climate change’
The month of June was the hottest in England on record, driven by a searing heatwave in the final days of the month, which for the first time had red heat alerts for three days, according to Met Office data.
The Met Office said provisional statistics showed Wales and the UK as a whole had recorded their second-warmest June since 1884.
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An eight-month expedition will set off soon from Norway on a mission to find new species before the climate crisis and pollution changes the northern ocean for ever
Six scientists and six crew will travel next month to Kirkenes, a remote Arctic town in Norway near the Russian border, to begin an odyssey to one of the most inhospitable, inaccessible and least-studied regions on Earth. There, they will climb onboard a futuristic, floating laboratory – the French-built Tara polar station.
They will enter a harsh and isolating environment: months of complete darkness and temperatures as low as -50C (-58F). Arriving in Norway on 14 August, they will await good conditions and an icebreaker to open a route for them before setting off on an eight-month voyage, overwintering through long, intense polar nights onboard a 26-metre-long, 16-metre-wide vessel built to be frozen into the pack ice, which will drift slowly over the north pole to Greenland.
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If we don’t know the source, not only do humans remain at risk but wildlife can suffer needlessly via retaliation
While virologists and public health departments were palpitating over the news of an Andes virus infectious disease outbreak on a cruise ship (13 cases, three deaths), in the Democratic Republic of the Congo the Bundibugyo virus, the root of the current Ebola outbreak (currently more than 1,250 cases and at least 362 deaths), was smouldering under the radar.
Bundibugyo virus is a horrifying, highly fatal pathogen. Symptom onset is sudden and includes headaches, diarrhoea, malfunctioning kidneys and liver, and, less frequently, internal and external bleeding (hence the term “haemorrhagic disease”). Grimly, contagiousness remains after death, meaning the family and loved ones of the deceased can be exposed when they wash and clothe the body in preparation for the funeral.
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New study on fluazinam’s neurotoxicity comes up with different findings from earlier report based on manufacturer’s data
Researchers who re-ran a crucial fungicide study on neurotoxicity have come up with significantly different findings, and campaigners argue that the substance should now be withdrawn from the market.
In 2005, a study conducted by Huntingdon Life Sciences on behalf of ISK, the manufacturer of fluazinam, on the development of neurotoxicity of fluazinam in pregnant rats concluded there were no statistically significant effects in relation to brain development in the rats’ offspring.
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We’re asking people from around the world to nominate their favourite spineless species for our third Invertebrate of the Year competition
Step aside World Cup heroes, there’s a bigger global competition in town. The whistle has been blown to launch the third Invertebrate of the Year contest.
We want you to nominate your favourite spineless creature for the hugely popular annual Guardian jamboree which celebrates the wonder and importance of the world’s invertebrates.
Continue reading...Many seabirds are starving to death as a marine heat wave lingers off California and fish seek deeper, cooler waters
Within minutes of walking on a San Diego beach, marine ornithologist Tammy Russell found the feathered carcasses – one after another.
Some were mixed in with washed up kelp. Others were under rocks.
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Poaching and wildfires have driven the country’s jaguar population to a critical level, and until now even rescued animals faced life in captivity
A tentative paw emerged from a steel cage on to the sandy riverbed deep in the Bolivian rainforest. Then, another. Slowly, the female jaguar looked right, left and right again, as if waiting to cross a busy road. Then, muscles stiff from the long journey, it strolled away and disappeared into the undergrowth.
Yaguara had been in captivity since August 2024, after being orphaned as an eight-month-old cub amid Bolivia’s worst recorded wildfire season. As the fires raged, burning more than 10% of the country’s surface area, authorities handed the cub over to a team of veterinarians from the Comunidad Inti Wara Yassi (CIWY), a wild-animal rescue centre.
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With probiotic foods thought to boost performance, tournament chefs are catering with gut health in mind
Trout sushi washed down with coffee kombucha may not be the stereotypical breakfast of champions, but it’s become the go-to for Wimbledon’s tennis stars.
Athletes are increasingly demanding sustainable options, as well as seeking out gut-friendly foods aligned with a microbiome diet, according to the tournament’s chefs. Recent research has shown a link between gut health, which can be improved through dietary changes, and sporting performance.
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Critics say the Trump administration is trying to rewrite and whitewash history by removing and altering scores of signs on public lands
Jerry Bransford, a former US National Park Service (NPS) ranger, has always had a deep connection with the land he grew up on – and the land hundreds of feet below it. His great-great-grandfather, Materson “Mat” Bransford, was one of the earliest explorers of Mammoth Cave in south-central Kentucky, the largest known cave system on the planet.
But for decades, Mat wasn’t paid for his work. Enslavers rented him out for $100 a year to a man who wanted to turn the site into a tourist attraction – what would later become Mammoth Cave national park.
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Study shows falling dust levels are making clouds more reflective, an effect not taken into account in climate models
Cleaner clouds are helping to slow the rate of global heating, a study shows. Falling levels of dust in the atmosphere are making clouds more reflective. This previously unidentified effect is not being taken into account by current climate models, which may mean they are slightly overestimating the projected rate of global heating.
Researchers analysed satellite observations of high clouds in the northern hemisphere and assessed the ratio of ice crystals to liquid droplets over the period 2008 to 2018. Their findings, published in Geophysical Research Letters, show that clouds have become less icy over that time. Weakening surface winds (due to climate change) have resulted in less dust being whipped up into the atmosphere over the last two decades. Dust particles help to seed ice crystals, so less dust means fewer ice crystals in clouds. The effect is not observed in southern hemisphere clouds because there is far less dust in the southern hemisphere atmosphere in the first place.
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Rezultati eNRGy ispitivanja, koje procjenjuje zenokutuzumab u solidnim tumorima pozitivnim na fuzije gena Neuregulin 1 (NRG1), izvijestili su o upravljivim nuspojavama i klinički značajnoj učinkovitosti - uključujući gotovo udvostručavanje preživljavanja bez progresije bolesti u usporedbi s očekivanjima uz standardnu njegu - kod prethodno liječenih pacijenata s uznapredovalim NRG1-pozitivnim kolangiokarcinomom.
Pacijentima s uznapredovalim rakom prostate mogu biti potrebne periodične slikovne snimke kako bi se otkrio rast tumora čak i sa stabilnim razinama prostata specifičnog antigena (PSA), proteina u krvi koji liječnici rutinski prate zbog progresije raka, pokazuje nova studija.
Velika prospektivna studija povezuje čaj, jabuke, naranče, bobičasto voće i drugu hranu bogatu flavonoidima sa smanjenim rizikom od raka dojke, uključujući i kod žena s povišenom genetskom predispozicijom.
Izgleda kako masna bolest jetre može potaknuti najagresivniji oblik metastatskog kolorektalnog karcinoma, pokazuje nova studija. Naime, rezultati, koji su objavljeni u časopisu Nature, ne samo da objašnjavaju zašto se neki pacijenti suočavaju s dramatično lošijim ishodima, već i ističu kako metabolička stanja poput masne bolesti jetre mogu izravno utjecati na napredovanje raka, otvarajući put preciznijim terapijama prilagođenim metaboličkom zdravlju pacijenta.
Nova studija je pokazala da primjena paracetamola (acetaminofena) tijekom trudnoće ne povećava rizik od razvoja poremećaja iz autističnog spektra (ASD) ili poremećaja hiperaktivnosti s nedostatkom pažnje (ADHD) kod djeteta.
Rezultati nove studije pokazali su da lijekovi agonisti GLP-1 receptora (GLP-1 RA) smanjuju broj smrtnih slučajeva, amputacija i hospitalizacija među osobama s dijabetesom tipa 2 koje su također imale sužene arterije nogu povezane s PAD-om (bolest perifernih arterija).
Liječnici imaju malo mogućnosti za pacijente koji razviju životno opasno plućno stanje zvano akutni respiratorni distres sindrom (ARDS). ARDS, čest uzrok smrti tijekom pandemije COVID-19, nastaje kada upalna kaskada izazvana infekcijom ili ozljedom propušta tekućinu u pluća, smanjujući razinu kisika u krvi. Nažalost, gotovo 40% pogođenih umire.
Viša razina vitamina A u cirkulaciji povezana je s boljom funkcijom pluća kod djece i odraslih s astmom, dok vitamin D pokazuje slične koristi kod odraslih, uključujući sporije biološko starenje, otkriva nova studija.
Visoke doze intravenskog (IV) vitamina C mogu smanjiti rizik od smrti i sepse kod pacijenata s traumom, kao i skratiti boravak u bolnici, sugeriraju rezultati nove studije.
Blokada imunoloških kontrolnih točaka (ICB) preoblikovala je krajolik liječenja uznapredovalog hepatocelularnog karcinoma (HCC), nudeći novu nadu tamo gdje je postojalo malo opcija. Međutim, samo manjina pacijenata postiže trajne odgovore, uglavnom zbog heterogenosti tumora, imunosupresivnog tumorskog mikrookruženja (TME) i primarne ili stečene otpornosti.