
Go Hvar go - ORGANIC!
© Vivian Grisogono 2014

Go Hvar go - ORGANIC!
© Vivian Grisogono 2014
East Midlands electric car club helps residents and cuts emissions – but the need for a volunteer-led scheme reflects a much wider problem
In the aftermath of the Covid pandemic Miriam Stoate, a regenerative farmer from rural Leicestershire, noticed that too many people in her small village in England’s East Midlands were struggling to get around.
Although there were plenty of cars parked in Tilton, too often she found some of the village’s residents did not have access to one when they really needed it.
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Sarah Eberle hopes to inspire people to nurture where town and countryside meet and nature is need of protection
Stinging nettles, buttercups, broken crockery, fly-tipped flowers and a discarded gnome are not the usual hallmarks of an RHS Chelsea flower show garden.
But this year’s On the Edge garden by Sarah Eberle – the most decorated designer at Chelsea – is designed not to look like a garden at all, rather to transport its visitors to the liminal spaces on the outskirts of towns where the countryside begins and nature is in critical need of protection.
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Emissions understated by factor of five in Essex plans for tech giant, while Greystoke’s Lincolnshire plans show similar error
Developers working for Google have significantly misstated how much carbon two proposed AI datacentres will contribute to the UK’s total emissions in planning documents reviewed by the Guardian.
The tech company wants to build two huge datacentres – one 52-hectare (130 acre) project in Thurrock and another at an airfield in North Weald, both in Essex. To do so, developers are required to submit planning documents calculating how much carbon these projects will emit as a proportion of the UK’s total carbon footprint.
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National Geographic photographer and WWF ambassador Jasper Doest joined conservation teams during the latest mountain gorilla census in Bwindi Impenetrable national park, taking pictures of the apes and the people essential to their survival
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With the war on Iran, Ukraine, AI and climate breakdown increasing the likelihood of a nuclear war, the clock stands closer to midnight than ever before. So who decides how many seconds we have left – and can we buy ourselves more time?
The Earth is getting hotter. Conflicts are raging, in the Middle East and Ukraine, each increasing the chance of nuclear war. AI is infiltrating almost every aspect of our lives, despite its unpredictability and tendency to hallucinate. Scientists, tinkering in labs, risk introducing new, deadly pathogens, more destructive than Covid. Our pandemic response preparedness has weakened. The Doomsday Clock – a large, quarter clock with no numbers, keeps ticking, counting down the seconds until the apocalypse. Tick. Tick. Tick. In January, we reached 85 seconds to midnight. Experts believe humanity has never stood so close to the brink.
“What we have seen is a slow almost sleepwalk into increasing dangers over the last decade. And we see these problems growing. We see science advancing at a rate that defies our ability to understand it, much less control it,” says Alexandra Bell, CEO of the Bulletin of the Atomic Scientists, the organisation that sets the Doomsday Clock. She speaks of the “complete failure in leadership” in the US and other countries, which are doing little to address global, catastrophic threats, even as they feed into one another. Climate change increases global conflict, for instance, and the incorporation of AI into nuclear decision-making is, frankly, terrifying.
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Findings come after third-hottest April on record globally and amid fears of more brutal European summer weather
Economic inequality adds more than 100,000 deaths to the vast toll from heat and cold in Europe each year, research has found.
Cutting levels of inequality to match that of Europe’s most equal region, Slovenia, as measured by the Gini index, would reduce temperature-related mortality by as much as 30%, equating to 109,866 people, the study found.
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Brigg, Lincolnshire: We work these vehicles hard and they will have problems, but today was really not the day for a steaming bonnet
There’s never a good time for a tractor to break down, but this was exceptional timing. Late April was very dry as predicted, and with a change in weather prospects, the birdfood seed needed to go in. The purpose of this “crop” is to fill the birds’ winter hunger gap, and it has to be sown in a narrow window: after the early May frosts, but before the soil dries out too much.
We had just delivered the trailer of seed to the field, and were on the road returning to the farm, to collect the rolls that press the seed into the soil. As we passed through Brigg, the lights appeared on the dashboard and steam started to appear from the bonnet. This was our smallest and newest tractor. Hurriedly, we pulled into a driveway, water pouring from under the engine. Half on and half off the road, we started to collect traffic behind us. A quick look justified a call to the tractor dealers – it was a tricky job and the clock was ticking.
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With the help of citizen scientists, researchers studying rare humpback ‘jaw-gaping’ believe the move could be a social display
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Off the coast of Western Australia, a humpback whale is “pirouetting”, sweeping its pectoral fins through the water, its massive jaw hanging wide open. Surrounded by companions, the animal isn’t lunging for a meal: rather, it is putting on a mysterious behavioural display.
This underwater ballet, captured on camera by an onlooker and shared online, is one of the clearest examples of a rarely documented phenomenon known as “gaping”.
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Warming ocean waters are priming beaches and raw shellfish for Vibrio even as scientists are trying to stay one step ahead
Bailey Magers and Sunil Kumar cut strange figures on Pensacola Beach. Bags of disinfectant solution surrounded them on the white sand; their gloved hands juggled test tubes while layers of rubber and plastic shielded their skin from the elements. As the two organized their seawater samples on the popular Florida shoreline last August, an older woman wearing a swimsuit walked over to ask what they were doing.
“We’re just actively monitoring water quality,” they told her, but she pressed on.
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Vitória Régia imagines rightwing Bolsonaro plot succeeded with US help – and highlights threats facing Indigenous peoples
The year is 2025 and far-right coup plotters have annihilated Brazil’s democracy, assassinating the president, closing the national congress and surrendering the Amazon rainforest and its untold riches to the United States.
“Ladies and gentlemen, welcome to the Amazon of America,” a thick-accented North American soldier tells a group of journalists being taken on a propaganda tour of an oil refinery in the newly annexed jungle realm. Nearby, a replica of the Statue of Liberty has been carved out of the wilderness to celebrate Washington’s tutelage over more than half of Brazil.
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Nedavno objavljena studija sugerira da bi široko korišteni lijek za astmu, formoterol, potencijalno mogao ponuditi sasvim drugačiji terapijski put te da bi se mogao koristiti za liječenje steatohepatitisa povezanog s metaboličkom disfunkcijom (MASH). Formoterol je agonist beta-2 adrenergičkih receptora koji se desetljećima propisuje za otvaranje dišnih putova kod stanja poput astme i kronične opstruktivne plućne bolesti (KOPB).
Desetljećima su liječnici i znanstvenici mislili da metformin, vodeći lijek za liječenje dijabetesa tipa 2 koji uzimaju milijuni ljudi diljem svijeta, uglavnom cilja jetru kako bi suzbio proizvodnju glukoze. No, nova studija je otkrila da se ovaj lijek umjesto toga prvenstveno fokusira na crijeva, djelujući tako da sprječava porast razine glukoze u krvi potičući iskorištavanje glukoze unutar stanica koje oblažu crijeva.
Prema rezultatima novog istraživanja, izgleda da hormoni povezani s muškim razvojem mogu igrati ključnu ulogu u ograničavanju rasta tumora mozga kod muškaraca. Naime, otkriveno je da gubitak androgenih hormona, poput testosterona, u predkliničkom modelu glioblastoma potiče rast tumora izazivanjem lokalne upale i poticanjem proizvodnje hormona stresa.
Nova studija sugerira da socijalna i profesionalna podrška mogu pomoći odraslima s dijabetesom tipa 2 da se pridržavaju vremenski ograničenog obrasca prehrane, prehrambene intervencije koja je pokazala obećavajuće rezultate u poboljšanju glikemijske kontrole i upravljanja tjelesnom težinom.
Nedavna studija temeljena na modelu miša sugerira da blokiranje TGF-β može poboljšati liječenje osteoporoze pomažući mirujućim osteoblastima na neaktivnim površinama kostiju da se vrate u aktivno stanje. Koristeći prostornu transkriptomiku, analizu pojedinačnih stanica i funkcionalne eksperimente, znanstvenici su identificirali TGF-β signalizaciju kao regulator aktivacije osteoblasta. U modelu miša s gubitkom kostiju, dvostruka inhibicija TGF-β i sklerostina povećala je koštanu masu učinkovitije od same inhibicije sklerostina, ističući obećavajuću strategiju kombiniranja.
Veći unos soje i mahunarki u prehrani povezan je s nižim rizikom od visokog krvnog tlaka (hipertenzija), otkriva nova analiza više studija. Optimalna dnevna količina može biti oko 170 g mahunarki, koje uključuju grašak, leću, slanutak i grah, te 60 do 80 g sojine hrane, primjerice tofu, sojino mlijeko, edamame, tempeh i miso.
Sindrom kratkog QT intervala je genetska bolest koja dovodi do iznenadne srčane smrti u mladoj dobi. Mutacije u genu SLC4A3, koji regulira izmjenu bikarbonata i klorida, nedavno su opisane kao potencijalni uzrok.
Američki znanstvenici identificirali su genetski sindrom u kojem neobično duge telomere - zaštitne kape na krajevima kromosoma - omogućuju imunološkim stanicama da ostanu biološki mlađe dulje od normalnog, predisponirajući pogođene osobe za limfom i druge vrste raka.
Imunoterapija raka temelji se na jednostavnoj, ali snažnoj ideji: imunološki sustav može prepoznati i uništiti stanice raka ako je pravilno aktiviran. Međutim, kod mnogih pacijenata taj je odgovor preslab ili prespor da bi bio učinkovit.
Novo istraživanje pokazuje da su isti geni aktivni kod raka gušterače, pretilosti i dijabetesa, što pomaže objasniti zašto se ljudi s metaboličkim bolestima često suočavaju s lošijim ishodima raka i ukazuje na buduće načine predviđanja recidiva i razvoja ciljanijih tretmana.